Dietary potassium and the development of hypertension in two-kidney, one clip Goldblatt hypertensive rats.
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چکیده
منابع مشابه
Effect of potassium chloride on the blood pressure in two-kidney, one clip Goldblatt hypertensive rats.
The effects of potassium loading on blood pressure (BP) and the renin-angiotensin-aldosterone system were investigated in two-kidney, one clip Goldblatt hypertensive rats. Two series of experiments were performed: one was begun just after renal artery constriction, and the other, after hypertension had developed. Potassium loading significantly attenuated the development of hypertension, and wa...
متن کاملبررسی اثرات تزریق سوبسترای رنین در هسته آمیگدال مرکزی بر فشارخون شریانی و ضربان قلب در موش صحرایی مبتلا به پرفشاری خون کلیوی ـ عروقی
Introduction & Objectives: Previous studies have revealed that induction of two kidney-one clip (2K1C) Goldblatt hypertension in rats eliminates hypertensive response after inactivating of the Central Nucleus of the Amygdala (CA). The present study investigated the possibility of alteration in local Renin Angiotensin System (RAS) activity in CA after hypertension induction and evaluation of car...
متن کاملEffects of Low-dose Morphine on Nitric Oxide Concentration and Angiogenesis in Two-kidney One Clip Hypertensive Rats
Objective(s) We investigated the effects of low-dose morphine on nitric oxide (NO) and angiogenesis in two-kidney one clip hypertensive (2K1C) rats. Materials and Methods Male rats were divided into two groups: sham-clip operated and 2K1C. Each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. Blood pressure, heart rate, plasma renin activity (PRA), NO concentration an...
متن کامل[Angiotensin-converting enzyme activity of the aorta in experimental hypertensive rats].
Angiotensin-converting enzyme activity of the aortic subcellular fractions (homogenate, mitochondria, microsomes and supernatant) was determined in normotensive and experimental hypertensive rats (1-clip, 1-kidney Goldblatt hypertensive; 1-clip, 2-kidney Goldblatt hypertensive and 2-clip, 2-kidney hypertensive rats). The systolic blood pressure markedly elevated in each group of experimental hy...
متن کاملبررسی پاسخدهی عروق مزانتر به آنژیوتانسین I و II در خلال ایجاد پرفشاری خون دو کلیه ای گلدبلات و اثر کاپتوپریل بر آن
Essential hypertension is one of the risk factors of cardiovascular diseases. Hypertension etiology is not completely known, it seems that rennin-Angiotensin system has an important role in its etiology, Thus better recognition of this system and its activity changes or vascular reaction changes to different parts of this system during progressive hypertension can be more effective in better re...
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ورودعنوان ژورنال:
- Hypertension
دوره 5 4 شماره
صفحات -
تاریخ انتشار 1983